Circhecw2
WebIntroduction: Circ_HECW2 plays a key role in lipopolysaccharide (LPS)-induced signal transduction, which is critical in osteoarthritis (OA). Thus, we analyzed the role of Circ_HECW2 in osteoarthritis. Methods: The expression of Circ_HECW2 and miR-93 was examined using reverse-transcription polymerase chain reaction. Cell apoptosis was … WebJul 27, 2024 · Particularly, Yao H et al. clarified that circHIPK2 and circHECW2 can modulate METH- or lipopolysaccharide-induced autophagy, respectively [3,9]. In our previous study, we confirmed several circRNAs via high-throughput RNA sequencing in primary cortical neurons treated with METH, among which circHomer1 was highly and …
Circhecw2
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WebJul 27, 2024 · Particularly, Yao H et al. clarified that circHIPK2 and circHECW2 can modulate METH- or lipopolysaccharide-induced autophagy, respectively [3, 9]. In our previous study, we confirmed several circRNAs via high-throughput RNA sequencing in primary cortical neurons treated with METH, among which circHomer1 was highly and … Web** P = 0.0076 versus UBC13 pull-down of circHECW2; ## P = 0.0011 versus UBC13 pull-down of Gapdh mRNA. g Immunoprecipitation showed the binding of FTO with UBC13 in bEnd.3 cells. Data were presented by three independent experiments. * P = 0.0210 versus vector. h The bEnd.3 cells were transfected with siUBC13, the level of Ubc13 mRNA was ...
http://jszy.seu.edu.cn/_upload/article/ae/fe/49f2c19844809e52bb8656152985/65ee2337-80ee-4190-b05f-f5c5bce58d32.pdf WebcircHECW2调控miR-30d-ATG5 轴. 基于信息学预测和实验验证,作者证明circHECW2通过竞争性抑制miR-30d,调控了ATG5介导的EMT作用过程。. 在体内模型中也进行了验证。. 本文提出的通路和模型为解释Meth或LPS处理导致的EMT过程提供了比较有说服力的机制解释,为将来开发阻断 ...
WebJul 23, 2024 · 2024年12月20日,Autophagy:circHECW2通过竞争性结合miR-30d,促进ATG5表达,ATG5以非自噬的作用途径影响EMT过程,参与血脑屏障完整性的调控。[2] 图2 NOTCH1途径参与circHECW2-miR-30d-ATG5轴调控的EndoMT. 2024年11月9日,Molecular Psychiatry: circDYM调控抑郁样行为。[3] WebMay 21, 2024 · Another study showed that circHECW2 regulated the endothelial-mesenchymal transition (EMT) via binding miR-30d and upregulating ATG5. 112 Delivery of circHECW2 siRNA in the mouse hippocampus ...
WebOur study demonstrated that circHECW2 regulated the EndoMT by directly binding to MIR30D, a significantly downregulated miRNA from miRNA profiling, which subsequently …
WebcircHECW2 hsa_circ_0002150 HECW2 8.349 1.03E-30 intronic circEXOG hsa_circ_0064889 EXOG 3.597 1.08E-155 exonic circG3BP1 hsa_circ_0006694 G3BP1 2.960 9.80E-91 exonic circPOLD1 hsa_circ_0052012 POLD1 2.527 5.02E-179 exonic circFGFR1 hsa_circ_0008016 FGFR1 2.086 9.60E-208 exonic circRIPK2 … handy touchscreen reagiert nichthttp://www.ncvar.org/RefCirc/detail.php?circid=825 handy top 10 2022Web** P = 0.0076 versus UBC13 pull-down of circHECW2; ## P = 0.0011 versus UBC13 pull-down of Gapdh mRNA. g Immunoprecipitation showed the binding of FTO with UBC13 in bEnd.3 cells. Data were presented by three independent experiments. * P = 0.0210 versus vector. h The bEnd.3 cells were transfected with siUBC13, the level of Ubc13 mRNA was ... business longevity statisticsWebThe in vivo relevance was confirmed as microinjection of circHecw2 siRNA lentivirus into the mouse hippocampus suppressed the EndoMT induced by LPS. These findings provide novel insights regarding the contribution of circHECW2 to the nonautophagic role of ATG5 in the EndoMT process in the context of drug abuse and the broad range of ... business longevity meaningWebView detailed information about property 182 Steeplechase Cir, Waxhaw, NC 28173 including listing details, property photos, school and neighborhood data, and much more. business long hair menWebAn enrichment of circHECW2 in the MIR30D-captured fraction compared with that observed following the introduction of mutations that disrupt base paring between circHECW2 and MIR30D. By applying a biotin-labeled specific probe, MIR30D was pulled down by circHECW2. ceRNA target : ATG5: Reference: Pubmed ID handy tools to share filesWebAn enrichment of circHECW2 in the MIR30D-captured fraction compared with that observed following the introduction of mutations that disrupt base paring between circHECW2 and … handy tools for home