WebGranulomatosis with polyangiitis (GPA), (previously Wegener's Granulomatosis) is an autoimmune disorder characterized by granulomatous necrotizing vasculitis that typically affects small and/or medium sized blood vessels in the orbit, respiratory tract (sinuses, nose, throat, lungs), and kidneys. WebGranulomatosis with polyangiitis often begins with inflammation of small- and medium-sized blood vessels and tissues in the nose, sinuses, throat, lungs, or kidneys. The cause is unknown. The disorder usually begins with nosebleeds, nasal congestion with crusting, sinusitis, hoarseness, ear pain, fluid in the middle ear, eye redness and pain ...
Cardiac Involvement in Granulomatosis With Polyangiitis …
Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs and kidneys. Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis. It slows blood flow to … See more Signs and symptoms of granulomatosis with polyangiitis can develop suddenly or over several months. The first warning signs usually involve your sinuses, throat or lungs. The … See more Granulomatosis with polyangiitis can occur at any age. It most often affects people between the ages of 40 and 65. See more The cause of granulomatosis with polyangiitis isn't known. It's not contagious, and there's no evidence that it's inherited. The condition can lead to inflamed, narrowed blood vessels and harmful inflammatory … See more Besides affecting your nose, sinuses, throat, lungs and kidneys, granulomatosis with polyangiitis can affect your skin, eyes, ears, heart and other organs. Complications might include: 1. Hearing loss 2. Skin scarring … See more WebFeb 4, 2024 · Granulomatosis with polyangiitis (previously Wegener’s granulomatosis) is a rare systemic inflammatory disease that can affect any organ but more commonly the sinuses, lungs, kidneys, and eyes. Ophthalmological disease is the manifesting feature of GPA in 8–16 % of patients but develops in an estimated 50–60 % of patients (Pakrou et … tryfitform
Granulomatosis with Polyangiitis - Vasculitis Foundation
WebGranulomatosis with polyangiitis (GPA) is a condition that causes inflammation that primarily affects the respiratory tract (including the lungs and airways) and the kidneys. This disorder is formerly known as Wegener granulomatosis. A characteristic feature of GPA is inflammation of blood vessels (vasculitis), particularly the small- and ... WebGranulomatosis with Polyangiitis is a disease involving granulomatous inflammation, necrosis and vasculitis that most frequently targets the upper respiratory tract, lower … WebOct 17, 2024 · Granulomatosis with Polyangiitis (Wegener's Granulomatosis): Evolving Concepts in Treatment. Semin Respir Crit Care Med. 2024 Aug. 39 (4):434-458. [QxMD MEDLINE Link]. Greco A, Marinelli C, Fusconi M, Macri GF, Gallo A, De Virgilio A, et al. Clinic manifestations in granulomatosis with polyangiitis. Int J Immunopathol … philip wear conservatories